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Elastin and Collagen in the Normal and Obstructed Urinary Bladder
Author(s) -
CORTIVO R.,
PAGANO F.,
PASSERINI G.,
ABATANGELO G.,
CASTELLANI I.
Publication year - 1981
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1981.tb03151.x
Subject(s) - elastin , pathological , ageing , urinary bladder , urinary system , bladder outlet obstruction , medicine , urology , pathology , prostate , cancer
SUMMARY— Histological and chemical studies were carried out on the elastin and collagen content of the normal and the obstructed urinary bladder wall. The observations were made on 3 different age groups: (1) 3‐month‐old children with vesical outlet obstruction, (2) children aged between 4 and 8 years with partial vesical obstruction, and (3) adults with a chronically obstructed bladder. An increase in elastic tissue was shown only in the newborn and in the adults. The collagen did not vary in any of the cases studied. The elastin showed an increase in polar amino acids in the pathological organs compared with the normal. A similar increase in elastin was observed in normal individuals as a result of the ageing process.