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Bilateral Germ Cell Tumours of the Testis
Author(s) -
SOKAL M.,
PECKHAM M. J.,
HENDRY W. F.
Publication year - 1980
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1980.tb02947.x
Subject(s) - seminoma , dysgerminoma , teratoma , medicine , chemotherapy , stage (stratigraphy) , germ cell , pathology , biology , ovary , paleontology , biochemistry , gene
Summary— Between 1952 and 1976, 760 men with testicular tumours were seen at The Royal Marsden Hospital. Of this group 21 (2.75%) developed tumours of the contralateral testis, in 2 instances synchronously and in the remaining 19 at intervals from 4 months to 15 years. Of 15 men in whom adequate history had been obtained, 7 (46%) had a history of maldescent and in all 7 patients the pathology of both tumours showed the same histological sybtype. Only one example of malignant teratoma undifferentiated (MTU) as first tumour was encountered; 13 of 19 (68%) patients had seminomas and the second tumour was a seminoma in 11 patients (58%). Of the group of 21 patients, 12 (57%) are alive and disease‐free. Of 14 Stage 1 patients (second tumour), 12 (85%) are considered cured of their 2 tumours. However, patients with evidence of extratesticular spread did badly, even if the second tumour was a seminoma, and treatment for these patients should include chemotherapy. Similarly, both State 1 MTU second tumours did badly.