Premium
The Role of Surgery in the Combined Management of Metastases from Malignant Teratomas of Testis
Author(s) -
HENDRY W. F.,
BARRETT ANNE,
McELWAIN T. J.,
WALLACE D. M.,
PECKHAM M. J.
Publication year - 1980
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1980.tb02917.x
Subject(s) - medicine , vinblastine , radiation therapy , chemotherapy , bleomycin , surgery
Summary— Thirty‐three patients with malignant testicular teratomas and para‐aortic metastases exceeding 2 cm in diameter have been treated with radiotherapy, chemotherapy (vinblastine and bleomycin, with or without cis–platinum) or both, followed by surgical excision of the residual para‐aortic mass. Removal of a poorly functioning ipsilateral kidney was necessary in 7 cases (21%) and a segment of vena cava was resected in 2 (12.5%) of 16 patients with primary right‐sided tumours. Removal was incomplete in only one patient, who had femoral nerve root involvement, and he subsequently died of secondary haemorrhage (operative mortality 3%). Undifferentiated tumour was found in 8 (61%) of 13 patients (Group 1) after radiotherapy, compared with only 2 (15%) of 13 (Group 2) after chemotherapy and radiotherapy, and 4 (57%) of 7 (Group 3) who had chemotherapy only prior to surgery; however, 3 of the Group 3 patients were referred because of evidence of activity in the para‐aortic region.