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Interstitial Cystitis
Author(s) -
ROSIN R. D.,
GRIFFITHS T.,
SOFRAS F.,
JAMES D. C. O.,
EDWARDS L.
Publication year - 1979
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1979.tb03593.x
Subject(s) - interstitial cystitis , etiology , medicine , autoantibody , human leukocyte antigen , pathology , immunology , urinary system , antigen , antibody
Summary— Twenty histologically proven cases of interstitial cystitis were investigated in an attempt to find evidence of a possible autoimmune mechanism in its aetiology. HLA tissue typing was performed, autoantibody profiles were obtained, and a questionnaire of the patients' past history completed, especially with respect to other autoimmune conditions. An experiment was designed to test the effect of sodium cromoglycate on rat bladders. The results are discussed in relation to the management of patients with interstitial cystitis.