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Pre‐operative Arterial Embolisation in Renal Carcinoma
Author(s) -
ARKELL D. G.,
COTTER K. PAULE,
FITZPATRICK J. D.,
SHAW R. E.
Publication year - 1978
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1978.tb06193.x
Subject(s) - medicine , nephrectomy , renal artery , renal cell carcinoma , renal carcinoma , surgery , occlusion , embolization , kidney , urology , carcinoma , caproic acid , chemistry , organic chemistry
Summary— Nephrectomy for carcinoma is often accompanied by moderate or severe bleeding but this may be reduced by prior occlusion of the renal artery. Embolisation with fresh autologous clot is rendered ineffective by rapid lysis. In vitro experiments showed that the clot could be stabilised by the addition of epsilon amino caproic acid (EACA). By injecting stabilised clot into the renal artery, satisfactory devascularisation of kidney and tumour was achieved in 10 patients.