Premium
The Effect of Allopurinol on Urinary Oxalate Excretion in Stone Formers
Author(s) -
SCOTT R.,
PATERSON P. J.,
MATHIESON A.,
SMITH M.
Publication year - 1978
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1978.tb06190.x
Subject(s) - allopurinol , oxalate , urine , excretion , urinary system , medicine , uric acid , urinary stone , drug , chemistry , urology , pharmacology , organic chemistry
Summary— Allopurinol is a drug which could be valuable in the treatment of stone patients. In 29 subjects treated with 300 mg of the drug per day it has been found that there was a significant fall in urine oxalate excretion if the blood urate was above 330 μmol/l. In 10 subjects followed for 1 year the urine oxalate was significantly reduced and maintained at a lower level than the original.