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An Evaluation of Techniques Used for the Production of Temporary Renal Ischaemia *
Author(s) -
McLOUGHLIN G. A.,
HEAL M. R.,
TYRELL I. M.
Publication year - 1978
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1978.tb04212.x
Subject(s) - renal artery , inulin , medicine , ischemia , renal function , occlusion , kidney , cardiology , renal ischemia , intracellular , chemistry , biochemistry , reperfusion injury
Summary— Five techniques of producing temporary renal ischaemia have been evaluated in the rat. Damage was assessed by measuring inulin clearance, change in renal cortical intracellular water and 125 l‐fibrin deposition. Continuous renal artery occlusion produces significantly less renal damage than the other techniques commonly used.