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Procarbazine (Natulan) in the Treatment of Peyronie's Disease
Author(s) -
MORGAN R. J.,
PRYOR J. P.
Publication year - 1978
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1978.tb03038.x
Subject(s) - peyronie's disease , procarbazine , medicine , dermatology , disease , chemotherapy , vincristine , cyclophosphamide
Summary— Thirty‐four men with Peyronie's diseases were treated with a 12‐week course of the drug procabazine (Natulan), preceded or followed by a 12‐week course of vitamin E. Ninety‐one per cent of the men failed to improve or became worse whilst receiving Natulan and toxic side‐effects were common. In comparision 39% improved whilst taking vitamin E. We conclude that Natulan is of little benefit in the treatment of this condition and may indeed be harmful.