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The Role of Bone Scanning in the Assessment of Prostatic Carcinoma
Author(s) -
McGREGOR B.,
TULLOCH A. G. S.,
QUINLAN M. F.,
LOVEGROVE F.
Publication year - 1978
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1978.tb02798.x
Subject(s) - medicine , radiology , carcinoma , bone marrow , prostate , bone imaging , nuclear medicine , pathology , cancer
Summary— Fifty new cases of carcinoma of the prostate were assessed prior to treatment to determine the incidence of bony metastases. The radioisotope bone scan was the most sensitive method of detecting metastases and of localising them. It was twice as accurate as the serum acid phosphatase estimation. Skeletal X‐rays were the least accurate method. Forty‐six per cent of patients had abnormal bone scans at presentation. The histological grade of the tumour correlated well with the bone scan. The higher the grade, the more likely was the bone scan to be abnormal. There is need for greater accuracy in detecting metastases, and the bone marrow acid phosphatase estimation, either alone or in conjunction with the bone scan, may provide this accuracy.