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Methyl Cholanthrene and Cadmium Induced Changes in Rat Prostate
Author(s) -
SCOTT R.,
AUGHEY E.
Publication year - 1978
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1978.tb02760.x
Subject(s) - cadmium , carcinogen , prostate , prostate cancer , cadmium exposure , endocrinology , medicine , chemistry , cancer , biology , biochemistry , organic chemistry
Summary— Cadmium workers have been thought to be more likely to develop prostatic cancer. The present study compares the effects of cadmium on rat prostate as compared with a known carcinogen, 20 methyl cholanthrene. The various histological effects produced are discussed. Possibly the most important aspect is the stratification and primitive clear cells found in rat prostatic acini in cadmium injected rats.