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Metastatic Orchioblastoma: Alpha 1 ‐fetoprotein in Diagnosis and Combination Chemotherapy in Treatment: a Case Report
Author(s) -
SMITH I. E.,
ECKSTEIN H. B.,
KOHN J.,
MCELWAIN T. J.
Publication year - 1977
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1977.tb04171.x
Subject(s) - hilum (anatomy) , medicine , laparotomy , chemotherapy , metastasis , alpha fetoprotein , lymph node metastasis , oncology , radiology , lymph node , pathology , cancer , hepatocellular carcinoma
A case in which orchioblastoma metastasised to a lymph node at the left renal hilum is described. The metastasis was not detected by bipedal lymphography, but was associated with a rise in the serum level of the alpha1-fetoprotein. The metastasis responded to combination chemotherapy, including adriamycin, and residual tumour was excised at laparotomy. Tumour regression was associated with a fall in serum alpha1-fetoprotein which may be of value as a tumour marker substance in the diagnosis and monitoring of therapy in this tumour.