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Studies of Hydrolytic Enzymes and Isoenzymes of Normal and Neoplastic Childhood Renal Tissues and their Tissue Cultured Cells
Author(s) -
WAGHE MADHAV,
KUMAR SHANT
Publication year - 1977
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1977.tb04100.x
Subject(s) - alkaline phosphatase , isozyme , acid phosphatase , enzyme , biology , wilms' tumor , kidney , biochemistry , phosphatase , pathology , microbiology and biotechnology , chemistry , medicine , endocrinology
The hydrolases of acid and alkaline phosphatase and non-specific esterases were investigated by histochemical and electrophoretic techniques in normal and neoplastic renal tissues and their cultured cells. A distinct tumour specific pattern of non-specific esterases was demonstrated in Wilms' tumour. The reasons for the quantitative differences found in the distribution of alkaline phosphatase in Wilms' tumour and their cultured cells are discussed.