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Hyperthermia in the Treatment of Bladder Tumours
Author(s) -
HALL R. R.,
WADEHRA V.,
TOWLER J. M.,
HINDMARSH J. R.,
BYRNE P. O.
Publication year - 1976
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1976.tb06707.x
Subject(s) - cystectomy , hyperthermia , medicine , urology , transitional cell carcinoma , irrigation , necrosis , bladder cancer , surgery , biology , cancer , agronomy
Summary High temperature bladder irrigation was employed in 4 men as an alternative to cystectomy because of their age and frailty. Hyperthermic irrigation of the bladder from 63°C for 70 minutes to 82°C for 25 minutes caused partial, but not total, necrosis of the bladder. Transitional cell carcinoma appears to be resistant in viw , in some cases, to heating at temperatures that destroy adjacent normal structures. Hyperthermic irrigation of the bladder at these high temperatures may be hazardous. In view of these findings we cannot recommend high temperature bladder irrigation as an alternative to cystectomy even in poor risk patients.