Premium
Chlorhexidine for Irrigation of Vas: a Clinical Trial and the Study of Viability of Non‐Motile Sperms in Post‐Vasectomy Patients with Trypan Blue Uptake
Author(s) -
YU H. Y. HENRY,
HALIM A.,
EVANS P. R.
Publication year - 1976
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1976.tb06655.x
Subject(s) - trypan blue , sperm , vasectomy , chlorhexidine , andrology , semen , irrigation , human fertilization , biology , medicine , zoology , anatomy , research methodology , population , agronomy , dentistry , biochemistry , cell , environmental health , family planning
Summary A clinical trial showed that when chlorhexidine was used for irrigation of a vas, 93% of patients became sperm‐free at 6 weeks as compared to 72%, when sterile water was used. The use of chlorhexidine for irrigation of the distal vas is recommended in order to achieve sterility within a shorter length of time in view of its potent spermicidal effect as compared with water. The determination of the viability of non‐motile sperms in post‐vasectomy patients by the method of trypan blue uptake is described. This is a simple laboratory procedure suitable for routine clinical use. The criteria for sterility after vasectomy should be based on either 2 consecutive sperm‐free specimens or 2 specimens of sperms shown to be 100% dead by trypan blue uptake.