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The Influence of Vesical Distension on Urethral Resistance to Flow: the Expulsion Phase
Author(s) -
GHONEIM M. A.,
FRETIN J. A.,
GAG D. J.,
SUSSET J. G.
Publication year - 1975
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1975.tb04034.x
Subject(s) - distension , reflex , urethra , atropine , propranolol , urology , medicine , anatomy , anesthesia , surgery
Summary The influence of vesical distension of the urethral pressure profile was studied in female dogs, using a model in which the bladder and urethra were separated. There was a reduction in the urethral resistance involving its smooth and striated muscle components. This reduction was completely blocked by ganglion blocking agents. Atropine did not influence these changes. Propranolol could only partially block this reflex. The other possible mechanisms that could be involved were discussed.