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A Study of the Bladder Blood Flow During Distension in Rabbits
Author(s) -
DUNN M.
Publication year - 1975
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1975.tb03919.x
Subject(s) - distension , blood flow , medicine , urinary bladder , urology , hypoxia (environmental) , blood pressure , bladder tumor , chemistry , bladder cancer , oxygen , organic chemistry , cancer
Summary This study has shown that there is a linear relationship between bladder blood flow and bladder pressure. At a bladder pressure of 80 mm Hg (blood pressure in rabbits varying from 90/60100/70 mm Hg) the blood flow in the bladder is minimal. It is suggested that bladder distension at 80 mm Hg in rabbits leads to hypoxia in the bladder wall as a result of the reduced blood flow. Prolonged bladder wall hypoxia occurring as a result of prolonged bladder distension may be responsible for selective necrosis of bladder tumours.