Premium
Sodium Excretion after Relief of Urinary Tract Obstruction in Children
Author(s) -
GHAZALI S.,
BARRATT T. M.
Publication year - 1974
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1974.tb03738.x
Subject(s) - excretion , nephron , renal sodium reabsorption , urinary system , reabsorption , medicine , endocrinology , urology , kidney , renal physiology , sodium , chemistry , organic chemistry
SUMMARY After relief of obstructive nephropathy urinary sodium excretion rose in 39 of 50 children to a mean in the whole group of 59% above preoperative levels. There was a significant positive correlation between the increase in sodium excretion in the first 24 hours after operation and the increase in GFR at 1 week. The data are compatible with the hypothesis that the reversibly obstructed kidney is characterised by nephron underperfusion and enhanced proximal reabsorption of filtrate due to hydrodynamic factors.