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The Effect of Progesterone on the Adrenergic Receptors of the Urethra 1
Author(s) -
RAZ SHLOMO,
ZEIGLER MARCIA,
CAINE MARCO
Publication year - 1973
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1973.tb12129.x
Subject(s) - adrenergic , urethra , adrenergic receptor , endocrinology , medicine , receptor , adrenergic agent , chemistry , urology
Summary A series of urethral pressure profile studies was performed on dogs, to investigate the effect of pre‐treatment with progesterone on the adrenergic responses. The results obtained indicate that progesterone facilitates or enhances the β‐adrenergic response. The possible mechanism by which this effect is produced is discussed. It is suggested that this modification of the adrenergic response of the urethra may partly explain the beneficial results reported in prostatic obstruction.