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THE PROSTATE AND THE ENDOCRINES: A Control Series *
Author(s) -
Clarke Ruscoe
Publication year - 1937
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1937.tb06620.x
Subject(s) - prostatectomy , medicine , endocrine system , urology , series (stratigraphy) , prostate , surgery , hormone , paleontology , cancer , biology
Summary1 A number of theories have been devised to explain prostatic hypertrophy on an endocrine basis. None of these have been proved. 2 A number of endocrine preparations are in use in an attempt to replace surgery. 3 Such therapy is still in the experimental stage, and as in other experimental work, accurate controls are desirable. 4 A series of 93 cases of prostatic obstruction, treated by neither prostatectomy nor endocrines, is presented. 5 These cases had been followed over an average period of over four years. 6 A large number showed a sustained improvement after instrumentation alone. 7 This series may be regarded, ( a ) as a control series, ( b ) as a brief summary of the variability of the course of the disease without prostatectomy and as a reminder of the frequent apparent “cure” after minimal instrumentation. 8 Conclusions as to the efficacy of endocrine or other new methods of treatment are only valid if cases are followed up for a considerable period of time. 9 The period suggested is five years.