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Insulin‐Like Immunoreactivity in the Neural Ganglion of the Ascidian Ciona intestinalis
Author(s) -
O'Neil G. S.,
Falkmer S.,
Thorndyke M. C.
Publication year - 1986
Publication title -
acta zoologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.414
H-Index - 37
eISSN - 1463-6395
pISSN - 0001-7272
DOI - 10.1111/j.1463-6395.1986.tb00858.x
Subject(s) - ciona intestinalis , biology , insulin , ganglion , ciona , antiserum , anatomy , neuroscience , microbiology and biotechnology , medicine , endocrinology , immunology , biochemistry , gene , antibody
Antisera raised against salmon insulin and bovine insulin were used to assess the distribution of insulin‐like immunoreactive neurons in the neural ganglion of Ciona intestinalis. Cell bodies of two sizes were found in cortical and medullary positions, together with an extensive network of immunoreactive fibres. These observations indicate that an insulin‐like material is an important component of the central nervous system in Ciona and gives weight to the hypothesis that protochordates utilize insulin‐like factors as neurotransmitters or modulators, as do their invertebrate ancestors.