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Effects of Hypophysectomy and Prolactin Replacement on Eel Kidney Structure During Adaptation to Sea Water
Author(s) -
Olivereau Madeleine,
Olivereau Jacqueline
Publication year - 1977
Publication title -
acta zoologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.414
H-Index - 37
eISSN - 1463-6395
pISSN - 0001-7272
DOI - 10.1111/j.1463-6395.1977.tb00244.x
Subject(s) - hypophysectomy , endocrinology , medicine , prolactin , biology , kidney , sodium , nephron , osmoregulation , hormone , chemistry , ecology , salinity , organic chemistry
After 20 to 50 days in sea water (SW), regressive changes of the kidney occur at the same rate in intact and hypophysectomized eels ( Anguilla anguilla ). In SW, ovine prolactin (oPRL) increases plasma electrolytes and restores a fresh water (FW) kidney structure; cell height and nuclear area increase in main segments of the nephron: first (P1) and second proximal (P2), distal (D) and initial collecting (C) tubules. A differentiation of new tubules also occurs. This effect is less intense after hypophysectomy and greater in FW. A dose of 10 μg/g body weight/day for 10 days in SW produces some harmful renal effects, barely detected at 6 μg/g/day. The kidney plays a minor role in osmotic adjustment in SW when PRL secretion is reduced (intact eels) or suppressed (hypophysectomized); PRL treatment reverses effects of SW adaptation. An inhibition of gill sodium extrusion may explain the high blood sodium level; however, kidney histological changes suggest a renal participation, perhaps through reduced water permeability as in Platichthys.