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A Mechanism of Action of Serotonin and Nor‐Adrenaline on the Regeneration of the Planarian Worm Dugesia tigrina
Author(s) -
Lenicque Pierre M.
Publication year - 1974
Publication title -
acta zoologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.414
H-Index - 37
eISSN - 1463-6395
pISSN - 0001-7272
DOI - 10.1111/j.1463-6395.1974.tb00190.x
Subject(s) - planarian , serotonin , biology , glycosaminoglycan , regeneration (biology) , mechanism (biology) , turbellaria , blastema , mechanism of action , anatomy , microbiology and biotechnology , endocrinology , medicine , biochemistry , receptor , philosophy , epistemology , in vitro
On the basis of autoradiographical investigations with tritiated serotonin or N adrenaline and histochemical studies, it was possible to describe a mechanism of cell migration in which these biogenic amines play a role in the presence of acid mucopolysaccharides and collagen. They may also have a role by provoking the formation of necrotic areas in which the mucopolysaccharides appear.