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Ocular myxoid leiomyosarcoma in a cat
Author(s) -
Labelle Philippe,
Holmberg Bradford J.
Publication year - 2010
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1111/j.1463-5224.2009.00749.x
Subject(s) - desmin , vimentin , enucleation , cytokeratin , glial fibrillary acidic protein , pathology , anatomy , leiomyosarcoma , eye enucleation , sma* , ciliary body , biology , metastasis , iris (biosensor) , medicine , immunohistochemistry , mathematics , combinatorics , cancer , genetics , computer security , computer science , biometrics
A case of myxoid leiomyosarcoma likely of iris dilator muscle origin in the enucleated eye of a 6‐year‐old domestic short haired cat is reported. The poorly demarcated mass expanded the iris, partially filled the globe and extended into the optic nerve. The mass was composed of spindle cells separated by abundant matrix positive for mucopolysaccharides with alcian blue. The neoplastic cells were immunoreactive for smooth muscle actin (SMA), S100 and vimentin, and negative for cytokeratin, Melan‐A, glial fibrillary protein (GFAP) and desmin. There was no evidence of recurrence or metastasis 6 months after enucleation.