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Meet the corneal myofibroblast: the role of myofibroblast transformation in corneal wound healing and pathology
Author(s) -
Myrna Kathern E.,
Pot Simon A.,
Murphy Christopher J.
Publication year - 2009
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1111/j.1463-5224.2009.00742.x
Subject(s) - myofibroblast , wound healing , pathology , cornea , fibroblast , medicine , biology , ophthalmology , surgery , fibrosis , in vitro , biochemistry
In recent years the role of the myofibroblast in corneal wound healing has been extensively studied. The transformation of the corneal keratocyte to the fibroblast and myofibroblast phenotypes is a critical process in normal and pathologic corneal wound healing. This review will introduce this important transformation and its role in corneal wound healing and pathology.