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Aspergillus flavus keratomycosis in a cat treated with topical 1% voriconazole solution
Author(s) -
Labelle Amber L.,
Hamor Ralph E.,
Barger Anne M.,
Maddox Carol W.,
Breaux Carrie B.
Publication year - 2009
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1111/j.1463-5224.2009.00673.x
Subject(s) - voriconazole , fungal keratitis , pathology , cornea , aspergillus flavus , cytology , aspergillosis , medicine , stromal cell , keratitis , corneal ulcer , microbiology and biotechnology , biology , ophthalmology , dermatology , immunology , antifungal
An 8‐year‐old male castrated Domestic Short‐haired cat was examined for a 1‐week history of blepharospasm and mucoid ocular discharge OS. Examination revealed ulcerative keratitis with stromal loss, stromal infiltrate, corneal edema, perilimbal vascularization and miosis. Cytology of the cornea revealed multiple dichotomously branching, septate fungal hyphae and severe, predominantly neutrophilic inflammation. PCR of the cytology samples confirmed the presence of Aspergillus flavus while fungal and bacterial cultures were negative. Treatment with topical 1% voriconazole solution was successful in resolving the keratomycosis.