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The cost‐effectiveness of insulin glargine vs. neutral protamine Hagedorn insulin in type 2 diabetes: a focus on health economics
Author(s) -
Levin P.
Publication year - 2008
Publication title -
diabetes, obesity and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.445
H-Index - 128
eISSN - 1463-1326
pISSN - 1462-8902
DOI - 10.1111/j.1463-1326.2008.00845.x
Subject(s) - insulin glargine , life expectancy , medicine , diabetes mellitus , insulin , protamine , public health , type 1 diabetes , intensive care medicine , type 2 diabetes mellitus , human insulin , cost effectiveness , type 2 diabetes , environmental health , endocrinology , risk analysis (engineering) , population , nursing , heparin
Diabetes mellitus is a major public health problem, in particular because of long‐term complications affecting essential organs, such as the eyes and kidneys, which can lead to a reduction in life expectancy and high healthcare costs. The number of individuals with diabetes mellitus is projected to rise worldwide from 171 million people in 2000 to 366 million people in 2030. With the number of patients with diabetes continually growing, the burden of pressure on worldwide health systems is huge. Accordingly, regulatory and marketing approvals of new medicines are beginning to incorporate economic evaluation techniques to determine their cost‐effectiveness. Overall, the studies included in this review show that the initiation of insulin glargine is cost‐effective and is expected to lead to substantial improvements in both life years (LYs) and quality‐adjusted LYs compared with neutral protamine Hagedorn insulin.