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Low‐dose oral tri‐iodothyronine does not directly increase food intake in man
Author(s) -
Martin N. M.,
Small C. J.,
Lee J. L.,
Ellis S.,
Dhillo W. S.,
Smith K. L.,
Kong W. M.,
Frost G. S.,
Bloom S. R.
Publication year - 2007
Publication title -
diabetes, obesity and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.445
H-Index - 128
eISSN - 1463-1326
pISSN - 1462-8902
DOI - 10.1111/j.1463-1326.2006.00613.x
Subject(s) - food intake , placebo , body weight , oral administration , medicine , endocrinology , triiodothyronine , zoology , physiology , biology , thyroid , pathology , alternative medicine
Previously, we have shown that low‐dose tri‐iodothyronine (T3) increases food intake in rodents. This randomised, double‐blind, placebo‐controlled study aimed to investigate the effects of low‐dose T3 on food intake in normal body weight individuals. However, despite an elevation in fT3 comparable to our earlier studies, administration of low‐dose T3 in the fasted state did not stimulate food intake in man.