Premium
Colorectal carcinoma in young adults: a retrospective study on Indian patients: 2000–2008
Author(s) -
Gupta S.,
Bhattacharya D.,
Acharya A. N.,
Majumdar S.,
Ranjan P.,
Das S.
Publication year - 2010
Publication title -
colorectal disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.029
H-Index - 89
eISSN - 1463-1318
pISSN - 1462-8910
DOI - 10.1111/j.1463-1318.2010.02223.x
Subject(s) - medicine , incidence (geometry) , colorectal cancer , retrospective cohort study , adenocarcinoma , cancer , young adult , presentation (obstetrics) , gastroenterology , general surgery , surgery , physics , optics
Aim To highlight an increased incidence of colorectal cancer (CRC) amongst young Indian adults. Method A retrospective study of 305 cases of CRC admitted to SSKM Hospital, Kolkata, India during 2000–2008 was carried out. Results The ratio (0.64) of under‐40 to above‐40 CRC patients reported in this study is comparable to those from premier Oncology Centers in India (∼0.52) and is higher than those in the Indian National Cancer Registry (∼0.20) and international average (0.07). Distinctive tumour characteristics in younger patients including left‐sided lesion (69.7%), presentation at an advanced (III/IV) stage (60%), poor histological differentiation (50%) and predominance of mucin‐secreting adenocarcinoma (80%) are similar to those reported in the international literature. Some features are suggestive of hereditary non polyposis colorectal cancer syndrome, which may be a possible reason for the high proportion of young CRC patients. Conclusion A high index of suspicion for CRC among young Indian adults is necessary.