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Comparison of standard vs high‐definition, wide‐angle colonoscopy for polyp detection: a randomized controlled trial
Author(s) -
Tribonias G.,
Theodoropoulou A.,
Konstantinidis K.,
Vardas E.,
Karmiris K.,
Chroniaris N.,
Chlouverakis G.,
Paspatis G. A.
Publication year - 2010
Publication title -
colorectal disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.029
H-Index - 89
eISSN - 1463-1318
pISSN - 1462-8910
DOI - 10.1111/j.1463-1318.2009.02145.x
Subject(s) - colonoscopy , medicine , hyperplastic polyp , adenoma , gastroenterology , endoscope , randomized controlled trial , high definition , colorectal cancer , radiology , cancer , computer science , computer hardware
Aim We sought to compare the performance of colonoscopy using a high‐definition, wide‐angle endoscope vs a standard colonoscope for the detection of polyps. Method A total of 390 patients were prospectively randomized into high‐definition colonoscopy group (HD, n = 193) and standard colonoscopy group (SC, n = 197). Results Analysis demonstrated that there were significant differences between the two groups, as far as the overall rate of polyps (SC, 1.31 ± 1.90; HD, 1.76 ± 2.31; P = 0.03) and the rate of small hyperplastic polyps (size < 5 mm; SC, 0.10 ± 0.36; HD, 0.25 ± 0.61; P = 0.003) were concerned. No significant differences between the two groups were observed, regarding large polyps (size ≥ 10 mm; SC, 0.39 ± 0.89; HD, 0.48 ± 0.80; P = 0.10), medium polyps (10 mm > size ≥ 5 mm; SC, 0.60 ± 1.46; HD, 0.58 ± 1.25; P = 0.31) and small polyps (size < 5 mm; SC, 0.32 ± 0.86; HD, 0.71 ± 1.65; P = 0.09). Similarly, no significant differences were demonstrated in the detection rate of adenomas and hyperplastic polyps, large adenomas, medium adenomas, small adenomas and large and medium hyperplastic polyps. Conclusion High‐definition colonoscopy led to a significant increase in the polyp detection.