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Prognostic analysis for carcinoid tumours of the rectum: a single institutional analysis of 106 patients
Author(s) -
Wang M.,
Peng J.,
Yang W.,
Chen W.,
Mo S.,
Cai S.
Publication year - 2011
Publication title -
colorectal disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.029
H-Index - 89
eISSN - 1463-1318
pISSN - 1462-8910
DOI - 10.1111/j.1463-1318.2009.02090.x
Subject(s) - medicine , rectum , general surgery , oncology
Aim Rectal carcinoid is a rare rectal tumour with a good prognosis. The aim of this study was to assess its clinicopathological characteristics and prognostic factors in a single institution. Method Clinical and pathological information was retrospectively collected in a single institution, and patients’ outcomes were determined. Multivariate analyses were performed to find independent prognostic factors attributed to overall survival. Results A total of 106 patients with rectal carcinoid were included. In all, 66% of the patients underwent transanal local excision and 34% had transabdominal surgery. The 5‐year survival rate was 87%. Muscularis invasion was the only independent prognostic factor for predicting 5‐year survival ( P = 0.00046). Tumour size was found to be significantly associated with muscular invasion ( P = 0.00003). The area under the curve of tumour size in the receiver operating characteristic curve for predicting muscular invasion was 0.92. Conclusion Patients with rectal carcinoid have a good prognosis. Muscular invasion is an independent risk factor of survival.