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Successful treatment of extensive splanchnic arterial and portal vein thrombosis associated with ulcerative colitis
Author(s) -
Di Fabio F.,
Obrand D.,
Satin R.,
Gordon P. H.
Publication year - 2009
Publication title -
colorectal disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.029
H-Index - 89
eISSN - 1463-1318
pISSN - 1462-8910
DOI - 10.1111/j.1463-1318.2008.01704.x
Subject(s) - medicine , thrombosis , splanchnic , ulcerative colitis , superior mesenteric artery , surgery , portal vein thrombosis , superior mesenteric vein , venous thrombosis , splenic vein , splanchnic circulation , radiology , cardiology , portal hypertension , blood flow , portal vein , cirrhosis , disease
Venous and arterial thromboembolism is a significant cause of morbidity and mortality in patients with ulcerative colitis (UC). Arterial thrombosis of the splanchnic region is a rare event with a very high mortality rate. Furthermore, it represents a challenging complication since it tends to be overlooked and misinterpreted as a clinical exacerbation of UC. We present the case of a 62‐year‐old female with pancolonic UC complicated by an extensive arterial thrombosis involving the aorta, the celiac trunk, the hepatic, gastric and splenic arteries and the superior mesenteric artery. A thrombosis of the splenic vein extending into the proximal portal vein was also present. The patient was successfully treated by a combined interventional‐radiological and surgical treatment. We discuss the rationale behind our management of this case and review the literature on splanchnic arterial thrombosis associated with UC.