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Ileostomy carcinomas a review: the latent risk after colectomy for ulcerative colitis and familial adenomatous polyposis
Author(s) -
Quah H. M.,
Samad A.,
Maw A.
Publication year - 2005
Publication title -
colorectal disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.029
H-Index - 89
eISSN - 1463-1318
pISSN - 1462-8910
DOI - 10.1111/j.1463-1318.2005.00807.x
Subject(s) - medicine , ileostomy , ulcerative colitis , familial adenomatous polyposis , colectomy , dysplasia , malignancy , gastroenterology , metaplasia , toxic megacolon , stoma (medicine) , incidence (geometry) , colorectal cancer , cancer , general surgery , disease , physics , optics
Background Ileostomy carcinoma after colectomy for ulcerative colitis and familial adenomatous polyposis is rare. Methods Forty‐three case reports from the literature and a case of ours are reviewed. Results The risk of malignancy following ileostomy formation appears to be increased compared to the very low incidence of primary small bowel carcinoma. Chronic physical or chemical irritation of the stoma may predispose the ileal mucosa to colonic metaplasia with subsequent adenoma formation, dysplasia and invasive malignant change. This is particularly so where ileostomies are fashioned for familial adenomatous polyposis and ulcerative colitis. Conclusion Routine surveillance of patients who have had an ileostomy for 15 years or longer may lead to earlier detection of this complication.