Open AccessIn vivo induced antigen technology (IVIAT)
Author(s) -
Rollins Sean M.,
Peppercorn Amanda,
Hang Long,
Hillman Jeffrey D.,
Calderwood Stephen B.,
Handfield Martin,
Ryan Edward T.
Publication year - 2005
Publication title -
cellular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.542
H-Index - 138
eISSN - 1462-5822
pISSN - 1462-5814
DOI - 10.1111/j.1462-5822.2004.00477.x
Subject(s) - biology , in vivo , virulence , antigen , gene , pathogen , pathogenesis , virology , immunology , computational biology , genetics
Summary In vivo induced antigen technology (IVIAT) is a technique that identifies pathogen antigens that are immunogenic and expressed in vivo during human infection. IVIAT is complementary to other techniques that identify genes and their products expressed in vivo . Genes and gene pathways identified by IVIAT may play a role in virulence or pathogenesis during human infection, and may be appropriate for inclusion in therapeutic, vaccine or diagnostic applications.