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One hundred times the intended dose of caudal clonidine in three pediatric patients
Author(s) -
MEYER CARI,
CAMBRAY RACHEL
Publication year - 2008
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.2008.02583.x
Subject(s) - clonidine , medicine , somnolence , anesthesia , depression (economics) , pediatrics , adverse effect , economics , macroeconomics
Summary We report three sequential cases in which children received 100 times the intended dose of clonidine in their single shot caudals. Although all experienced excessive somnolence for up to 24 h, none had respiratory depression, oxygen desaturation, supplemental oxygen requirement, or hemodynamic instability. These cases suggest a large margin of safety exists for caudally administered clonidine in healthy children.