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Tumor lysis associated with dexamethasone use in a child with leukemia
Author(s) -
OSTHAUS WILHELM ALEXANDER,
LINDERKAMP CHRISTIN,
BÜNTE CHRISTOPH,
JÜTTNER BJORN,
SÜMPELMANN ROBERT
Publication year - 2008
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.2008.02412.x
Subject(s) - medicine , antiemetic , dexamethasone , vomiting , nausea , anesthesia , postoperative nausea and vomiting , anesthesiology , leukemia , surgery
Summary Postoperative nausea and vomiting (PONV) occurs in every third patient undergoing general anesthesia without PONV prophylaxis. Antiemetic prophylaxis with dexamethasone is commonly used in patients at moderate risk. We present a case in which PONV prophylaxis with a single dose of dexamethasone led to tumor lysis in a patient with acute leukemia. In case of a cancer patient at moderate risk for PONV, the anesthesiologist should contact the oncologist first, or use other antiemetic drugs such as antiserotoninergic agents for PONV prophylaxis.