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Comparison of different near‐infrared spectroscopic cerebral oxygenation indices with central venous and jugular venous oxygenation saturation in children
Author(s) -
NAGDYMAN NICOLE,
EWERT PETER,
PETERS BJÖRN,
MIERA OLIVER,
FLECK THILO,
BERGER FELIX
Publication year - 2008
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.2007.02365.x
Subject(s) - medicine , limits of agreement , oxygenation , cardiology , venous blood , anesthesia , nuclear medicine
Summary Background: We compared two different near‐infrared spectrophotometers: cerebral tissue oxygenation index (TOI) measured by NIRO 200 and regional cerebral oxygenation index (rSO 2 ) measured by INVOS 5100 with venous oxygen saturation in the jugular bulb (SjO 2 ) and central SvO 2 from the superior caval vein (SVC) during elective cardiac catheterization in children. Methods: A prospective observational clinical study in 31 children with congenital heart defects in a catheterization laboratory was undertaken. TOI was compared with SjO 2 in the left jugular bulb and with SvO 2 . rSO 2 was compared with SjO 2 from the right jugular bulb and SvO 2 . Linear regression analysis and Pearson’s correlation coefficient were calculated and Bland–Altman analyses were performed. Results: Cerebral TOI and SjO 2 were significantly correlated ( r = 0.56, P < 0.0001), as well as TOI and SvO 2 with r = 0.74 ( P < 0.0001). Bland–Altman plots showed a mean bias of −4.3% with limits of agreement of 15.7% and −24.3% for TOI and SjO 2 and a mean bias of −4.9% with limits of agreement of 10.3% and −20.1% for TOI and SvO 2 . Cerebral rSO 2 and SjO 2 showed a significant correlation ( r = 0.83, P < 0.0001) and rSO 2 and SvO 2 showed excellent correlation with r = 0.93 ( P < 0.0001). Bland–Altman plots showed a mean bias of −5.2% with limits of agreement of between 8.4% and −18.8% for rSO 2 and SjO 2 and a mean bias of 5.6% with limits of agreement of 13.4% and −2.2% for rSO 2 and SvO 2 . Conclusions: Both near‐infrared spectroscopy devices demonstrate a significant correlation with SjO 2 and SvO 2 values; nevertheless both devices demonstrate a substantial bias of the measurements to both SjO 2 and SvO 2 .