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Minor increase of endtidal CO 2 during sevoflurane‐induced malignant hyperthermia
Author(s) -
BONCIU MONALISA,
DE LA CHAPELLE ARNAUD,
DELPECH HENRY,
DEPRET THIERY,
KRIVOSICHORBER RENEÉ,
AIMÉ MARC RAUCOULES
Publication year - 2007
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.2006.02051.x
Subject(s) - malignant hyperthermia , medicine , sevoflurane , dantrolene , contracture , anesthesia , halothane , hyperthermia , surgery , calcium
Summary Malignant hyperthermia (MH) in a pediatric patient during sevoflurane anesthesia with only a minor rise of endtidal CO 2 is described. MH was considered because of increased rectal temperature. The outcome was favorable after the initiation of a few simple measures (increased minute ventilation, cessation of sevoflurane). As recommended by the regional MH Reference Center, dantrolene was not used. In vitro contracture tests were performed on muscle biopsies from both parents. A strong contracture in response to halothane confirmed the father's MH susceptibility, thereby according a high probability of an MH episode in his son.