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Oral ketamine premedication can prevent emergence agitation in children after desflurane anaesthesia *
Author(s) -
Kararmaz Alper,
Kaya Sedat,
Turhanoglu Selim,
Ozyilmaz Mehmet Ali
Publication year - 2004
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.2004.01224.x
Subject(s) - premedication , medicine , anesthesia , ketamine , desflurane , fentanyl , emergence delirium , tramadol , tonsillectomy , incidence (geometry) , droperidol , surgery , analgesic , isoflurane , sevoflurane , physics , optics
Summary Background : The purpose of the present study was to determine whether oral ketamine premedication affected the incidence of emergence agitation in children. Methods : Thirty minutes before induction of anaesthesia, 80 children who were undergoing adenotonsillectomy with or without bilateral myringotomy and insertion of tubes received either ketamine 6 mg·kg −1 per oral in group K or sour cherry juice alone in group C. Anaesthesia was maintained with desflurane. Emergence and recovery times were recorded. Tramadol was used for postoperative analgesia. Fentanyl (1 μ g·kg −1 ) was administered for the treatment of emergence agitation or severe pain that still continued after tramadol administration. Postoperative behaviour was evaluated using a 5‐point agitation scale. Results : The incidence of emergence agitation was 56% in group C, and 18% in group K ( P = 0.001). There was no significant difference with respect to emergence times except from time to eye opening that was significantly longer in group K ( P < 0.0001). Conclusion : Oral ketamine premedication reduced the incidence of postanaesthesia emergence agitation in children without delaying recovery.