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Epidural sufentanil during paediatric cardiac surgery: effects on metabolic response and postoperative outcome
Author(s) -
BICHEL THIERRY,
ROUGE JEANCLAUDE,
SCHLEGEL SUZANNE,
SPAHRSCHOPFER ISABELLE,
KALANGOS AFKSENDIYOS
Publication year - 2000
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.2000.00557.x
Subject(s) - medicine , sufentanil , anesthesia , perioperative , incidence (geometry) , cardiac surgery , intensive care unit , mechanical ventilation , surgery , remifentanil , ventilation (architecture) , hemodynamics , opioid , propofol , mechanical engineering , physics , receptor , optics , engineering
The metabolic and neuroendocrine effects of caudal epidural analgesia were studied during paediatric cardiac surgery. Combined epidural and general anaesthesia (EPI group; n =12) was compared with deep opioid anaesthesia (DOA group; n =12). During anaesthesia and surgery, haemodynamic stability was similar in the two groups. There was no significant difference between groups concerning the metabolic response to surgery but circulating catecholamines were significantly lower in the EPI group during and after surgery. Perioperative release of IL‐6 was higher in the EPI group possibly reflecting a longer aortic clamp time. Incidence of postoperative life‐threatening dysrhythmias was very low in the two groups. No significant reduction of postoperative mechanical ventilation, intensive care unit or hospital stays was reported with epidural analgesia. The incidence of postoperative infections was higher than expected in the two groups because of the poor properative clinical status of most of the children included in the study.