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Safety and efficacy of semi‐closed circle ventilation in small infants
Author(s) -
PETERS J. W. B,
BEZSTAROSTIVAN EEDEN J,
ERDMANN W,
MEURSING A. E. E
Publication year - 1998
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.1998.00232.x
Subject(s) - medicine , anesthesia , fresh gas flow , ventilation (architecture) , cardiorespiratory fitness , oxygen , general anaesthesia , nitrous oxide , controlled ventilation , sevoflurane , mechanical engineering , chemistry , organic chemistry , engineering
The purpose of this clinical trial was to investigate the safety and efficacy of semi‐closed circle ventilation of the Dräger anaesthesia ventilators (Cicero, Cato), using a fresh gas flow (FGF) of 600 ml·min −1 . Twenty infants, weighing less than 6000 g, without cardiorespiratory abnormalities who required general anaesthesia of at least 30 min were included. The FGF was reduced to 600 ml·min −1 after 10 min of denitrogenation with a FGF of 4 to 6 l·min −1 . The composition of the FGF (600ml·min −1 ) was calculated as follows: oxygen necessary for consumption (60 ml·min −1 ) plus the remaining FGF in a 1:2 relationship for oxygen. The inspiratory nitrogen fraction was calculated to exclude accumulation. Inspiratory fractions of O 2 and N 2 O plus inspiratory and endtidal CO 2 partial pressures and noninvasive oxygen saturation were the control parameters. The gas concentrations (O 2 and N 2 O) remained within safe limits. Hypoxic gas concentrations were not observed. Neither nitrogen nor CO 2 accumulated in the circle system. In conclusion, low flow anaesthesia can be performed safely in infants under 6000 grams with the Dräger Cicero and Cato anaesthesia ventilators.