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Sevoflurane in paediatric anaesthesia: effects on respiration and circulation during induction and recovery
Author(s) -
MORI NAOHISA,
SUZUKI MASAHIRO
Publication year - 1996
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.1996.tb00368.x
Subject(s) - medicine , sevoflurane , anesthesia , respiration , halothane , general anaesthesia , respiratory system , anatomy
Summary This study examined induction and recovery times and respiratory and cardiovascular changes during induction and recovery in paediatric patients undergoing anaesthesia under spontaneous respiration induced with sevoflurane ( S group, n = 10) and halothane (H group, n = 9) at 2.4 MAC. F ET/ F I increased more rapidly, the incidence of breath holding and coughing was less and the recovery time was shorter in the S group compared with the H group. During induction with sevoflurane at 2.4 MAC, min vol/bodyweight decreased due to reduced tidal vol/bodyweight despite increased respiratory frequency, as with halothane at the same MAC. Slight decrease in blood pressure was observed during induction in the S group, while the circulatory depression was not observed during induction in the H group. These results suggest that sevoflurane is a suitable agent for induction under spontaneous respiration with higher concentrations in paediatric anaesthesia.