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Nitric oxide treatment for acute respiratory failure in children
Author(s) -
ALLMAN K.G.,
YOUNG J.D.,
STEVENS J.E.,
ARCHER L.N.J.
Publication year - 1994
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.1994.tb00398.x
Subject(s) - medicine , acute respiratory failure , anesthesia , oxygenation , paediatric intensive care unit , respiratory failure , nitric oxide , intensive care unit , adverse effect , pediatric intensive care unit , intensive care medicine , mechanical ventilation
Summary We have used nitric oxide in the treatment of four children admitted to the paediatric intensive care unit with acute, severe respiratory failure. Administration resulted in an improvement in arterial oxygenation range 1.3–18.4 kPa (9.9–140 mmHg): mean 6.7 kPa (51 mmHg) and a reduction in arterial carbon dioxide tension range 0.6–1.2 kPa (4.5–9 mmHg): mean 0.9 kPa (6.8 mmHg). No adverse effects were encountered following administration for a duration of 3–12 days at a dose of 40–64 parts per million.