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Vecuronium titration for muscle relaxation in myotonic dystrophy
Author(s) -
DIEFENBACH CHRISTOPH,
ABEL MANFRED,
BUZELLO WALTER
Publication year - 1994
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.1994.tb00142.x
Subject(s) - myotonic dystrophy , medicine , neuromuscular transmission , muscle relaxation , myotonia , neuromuscular disease , anesthesia , muscle relaxant , muscular dystrophy , nerve stimulator , disease
Summary A 14‐year‐old boy with pronounced myotonic dystrophy and cardiac malformation had a normal ED 95 (53 μg·kg −1 ) of vecuronium, whereas the recovery index (25‐75% twitch recovery) was three times as long as in the absence of neuromuscular disease. We conclude that in young patients with dystrophic muscle disease individual titration of the muscle relaxant with the aid of a nerve stimulator does not preclude a considerable delay in the recovery of neuromuscular transmission.