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Anaesthesia and the lipidoses: a review of patients treated by bone marrow transplantation
Author(s) -
MAHONEY A.,
SONI N.,
VELLODI A.
Publication year - 1992
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/j.1460-9592.1992.tb00201.x
Subject(s) - medicine , surgery , bone marrow transplantation , disease , general anaesthesia , intubation , tracheal intubation , transplantation , cardiorespiratory fitness , anesthesia
Summary There are many potential problems associated with anaesthesia in patients with lipid storage diseases. This review covers an 8‐year period (1983–1990) during which time 13 patients presented for procedures associated with bone marrow transplantation. The case notes of 12 patients who underwent a total of 48 general anaesthetics were reviewed. Pre‐operative assessment revealed cardiorespiratory disease in six patients. Eighty per cent of the children were anaemic (haemoglobin < 95 g1 ‐1 ). Anaesthesia was tolerated well although tracheal intubation in two patients with Gaucher's disease was difficult and became progressively more difficult as they became older. Forty‐five per cent of patients with Gaucher's disease were intubated with a tracheal tube smaller than predicted from the age of the child. Few complications were encountered but those which may be anticipated are discussed.