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Cell‐autonomous and cell‐to‐cell signalling events in normal and altered neuronal migration
Author(s) -
Manent JeanBernard,
Beguin Shirley,
Ganay Thibault,
Represa Alfonso
Publication year - 2011
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1111/j.1460-9568.2011.07867.x
Subject(s) - neuroscience , cerebral cortex , cortex (anatomy) , neuronal migration , premovement neuronal activity , biology , signalling , microbiology and biotechnology
The cerebral cortex is a complex six‐layered structure that contains an important diversity of neurons, and has rich local and extrinsic connectivity. Among the mechanisms governing the cerebral cortex construction, neuronal migration is perhaps the most crucial as it ensures the timely formation of specific and selective neuronal circuits. Here, we review the main extrinsic and extrinsic factors involved in regulating neuronal migration in the cortex and describe some environmental factors interfering with their actions.