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Extending lifetime of plastic changes in the human brain
Author(s) -
Nyffeler Thomas,
Wurtz Pascal,
Lüscher HansRudolf,
Hess Christian W.,
Senn Walter,
Pflugshaupt Tobias,
Von Wartburg Roman,
Lüthi Mathias,
Müri René M.
Publication year - 2006
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1111/j.1460-9568.2006.05154.x
Subject(s) - transcranial magnetic stimulation , neuroscience , plasticity , human brain , neuroplasticity , frontal cortex , stimulation , psychology , functional connectivity , cortex (anatomy) , computer science , physics , thermodynamics
The ability of the brain to adjust to changing environments and to recover from damage rests on its remarkable capacity to adapt through plastic changes of underlying neural networks. We show here with an eye movement paradigm that a lifetime of plastic changes can be extended to several hours by repeated applications of theta burst transcranial magnetic stimulation to the frontal eye field of the human cortex. The results suggest that repeated application of the same stimulation protocol consolidates short‐lived plasticity into long‐lasting changes.