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Corticofugal feedback for auditory midbrain plasticity elicited by tones and electrical stimulation of basal forebrain in mice
Author(s) -
Zhang Yunfeng,
Hakes Jacqueline J.,
Bonfield Stephan P.,
Yan Jun
Publication year - 2005
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1111/j.1460-9568.2005.04276.x
Subject(s) - inferior colliculus , neuroscience , basal forebrain , auditory cortex , forebrain , muscimol , midbrain , neuroplasticity , nucleus basalis , stimulation , cholinergic , nucleus , psychology , biology , central nervous system , agonist , receptor , biochemistry
The auditory cortex (AC) is the major origin of descending auditory projections and is one of the targets of the cholinergic basal forebrain, nucleus basalis (NB). In the big brown bat, cortical activation evokes frequency‐specific plasticity in the inferior colliculus and the NB augments this collicular plasticity. To examine whether cortical descending function and NB contributions to collicular plasticity are different between the bat and mouse and to extend the findings in the bat, we induced plasticity in the central nucleus of the mouse inferior colliculus by a tone paired with electrical stimulation of the NB (hereafter referred to as tone‐ES NB ). We show here that tone‐ES NB shifted collicular best frequencies (BFs) towards the frequency of the tone paired with ES NB when collicular BFs were different from tone frequency. The shift in collicular BF was linearly correlated to the difference between collicular BFs and tone frequencies. The changes in collicular BFs after tone‐ES NB were similar to those found in the big brown bat. Compared with cortical plasticity evoked by tone‐ES NB , the pattern of collicular BF shifts was identical but the shifting range of collicular BFs was narrower. A GABA A agonist (muscimol) or a muscarinic acetylcholine receptor antagonist (atropine) applied to the AC completely abolished the collicular plasticity evoked by tone‐ES NB . Therefore, our findings strongly suggest that the AC plays a critical role in experience‐dependent auditory plasticity through descending projections.