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Entorhinal cortex contributes to object‐in‐place scene memory
Author(s) -
Charles David P.,
Browning Philip G. F.,
Gaffan David
Publication year - 2004
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1111/j.1460-9568.2004.03777.x
Subject(s) - entorhinal cortex , perirhinal cortex , fornix , object (grammar) , psychology , hippocampus , cortex (anatomy) , artificial intelligence , computer vision , cognitive neuroscience of visual object recognition , neuroscience , computer science , cognitive psychology , recognition memory , cognition
Four rhesus monkeys ( Macaca mulatta ) were trained preoperatively in a test of object‐in‐place scene memory. They were presented daily with lists of unique computer‐generated scenes each containing a spatial array of multiple individual objects. Within each scene, objects to be discriminated appeared in the foreground, each occupying a unique location, and monkeys were required to correctly discriminate the rewarded object to receive a food reward. Once this preoperative criterion was attained, the monkeys received bilateral entorhinal cortex ablation performed as either one or two surgical operations with a period of testing following each. Postoperatively, they were significantly impaired in learning new object‐in‐place scene problems. These results show that the entorhinal cortex, like anatomically related structures including the perirhinal cortex and the fornix, contributes to object‐in‐place scene learning.