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Modular Connections between Areas V2 and V4 of Macaque Monkey Visual Cortex
Author(s) -
Zeki S.,
Shipp S.
Publication year - 1989
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1111/j.1460-9568.1989.tb00356.x
Subject(s) - macaque , wheat germ agglutinin , cytochrome c oxidase , horseradish peroxidase , cortex (anatomy) , visual cortex , projection (relational algebra) , biology , anatomy , biophysics , neuroscience , chemistry , microbiology and biotechnology , biochemistry , computer science , lectin , enzyme , algorithm
We have studied the connections between two visual areas of macaque monkey cortex, V2 and V4, by injecting wheat‐germ agglutinin horseradish peroxidase (HRP‐WGA) into V4 and examining the distribution of labelled cells and terminals in V2, in relation to its characteristically striped cytochrome oxidase architecture. The cells projecting from V2 to V4 are arranged in bands and the number of bands per cycle of cytochrome oxidase stripes varies (one cycle consists of a thin stripe, a thick stripe and two interstripes). In the Type 1 connectivity pattern, there is just one band per cycle, centred over the thin stripes but normally spreading into the neighbouring interstripes. In the Type 2 connectivity pattern there are two bands per cycle, generally rather narrower and centred over the interstripes. Thick stripes are mostly free of labelled cells. The return projection from V4 to V2, whilst being concentrated in the vicinity of the labelled cells, is more diffusely distributed and invades the territory of all the stripes.