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New horizon on successful management for a woman with repeated implantation failure due to unresponsive thin endometrium: Use of extended estrogen supplementation
Author(s) -
Shen MengShun,
Wang ChiaWoei,
Chen ChiHuang,
Tzeng ChiiRuey
Publication year - 2013
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2012.02070.x
Subject(s) - endometrium , medicine , implantation failure , estrogen , embryo transfer , pregnancy , in vitro fertilisation , controlled ovarian hyperstimulation , gynecology , obstetrics , infertility , biology , genetics
An adequate thickness and pattern of the pre‐ovulatory endometrium is considered one of the essential requirements for a successful pregnancy. Although various methods for increasing endometrial thickness have been proposed, the real value of these interventions remains controversial. Here, we present a case of successful administration of extended estrogen supplementation before conventional controlled ovarian hyperstimulation in a woman who had experienced repeated implantation failure because of an unresponsive thin endometrium. After the estrogen supplement was administrated for an extended period, the in vitro fertilization/embryo transfer in this patient led to an uneventful twin pregnancy and delivery at term.